吹扫捕集-气相色谱串联质谱法测定儿童防护口罩中残留环氧
岳大磊1,张子豪1,李全忠1,林海2,刘莹峰1,彭速标1,肖前1
1.广州海关技术中心,广州 510623; 2.湛江海关技术中心,广东湛江 524000
Determination of ethylene oxide and propylene oxide in protective masks for children by purge-and-trap-gas chromatography-tandem mass spectrometry
岳大磊1,张子豪1,李全忠1,林海2,刘莹峰1,彭速标1,肖前1
1. Guangzhou Customs Technology Center, Guangzhou 510623, China; 2. Zhanjiang Customs Technology Center, Zhanjiang 524000, China
摘要:采用吹扫捕集-气相色谱-串联质谱(P&T-GC-MS/MS)技术了测定儿童防护口罩中环氧乙烷、环氧丙采用吹扫捕集-气相色谱-串联质谱(P&T-GC-MS/MS)技术了测定儿童防护口罩中环氧乙烷、环氧丙烷的方法。样品采用4%乙酸水溶液作为模拟液浸泡处理,浸泡液中目标物通过吹扫富集于捕集管中,热脱附后进入气相色谱,采用DB-624 UI型色谱柱(60 m×0.25 mm, 1.40μm)分离,气相色谱串联质谱多反应监控模式进行分析检测,内标法定量。环氧乙烷、环氧丙烷在质量浓度为0.2~15 ng/mL范围内与色谱峰面积线性关系良好,环氧乙烷、环氧丙烷的相关系数分别为0.999 8、0.997 5,方法定量限均为0.01μg/g,满足GB/T 38880—2020及国外相关标准的限值要求。样品加标回收率为91.5%~115.7%,测定结果的相对标准偏差不大于4.9%(n=6)。该方法适用于儿童防护口罩中环氧乙烷、环氧丙烷消毒有效成分的批量测定。
Abstract:A method for the determination of ethylene oxide and propylene oxide in protective masks for children by A method for the determination of ethylene oxide and propylene oxide in protective masks for children by purge-and-trap coupled with gas chromatography-tandem mass spectrometry(P&T-GC-MS/MS) was established. The samples were soaked with 4% acetic acid as the simulated soaking solution. The target substances were enriched by the purge-and-trap, injected into gas chromatography after thermal desorption, separated on a DB-624 UI column(60 m×0.25 mm, 1.4μm), analysed by multi-reaction monitoring mode, and quanti旻搀 by internal standard. The mass concentration of ethylene oxide and propylene oxide had good linear relationships with their chromatographic peak area in the range of 0.2-15 ng/mL, with the correlation coef 揻椀攀渀琀猀 was 0.999 8 and 0.997 5, respectively, the limits of quantitation were all 0.01μg/g which could meet the limit requirements of GB/T 38880—2020 and relevant foreign standards. The spiked recoveries of samples was 91.5%-115.7%, and the relative standard deviations were not more than 4.9%(n=6). The method is suitable for the batch determination of ethylene oxide and propylene oxide in children's protective masks.
关键词:环氧类物质;儿童防护口罩;吹扫捕集;气相色谱串联质谱
Keywords:epoxides; children protective masks; purge-and-trap; gas chromatography-tandem mass spectrometry
基金:海关总署科研项目(2020HK236)
本文引用格式:
岳大磊,张子豪,李全忠.吹扫捕集-气相色谱-串联质谱法测定儿童防护口罩中环氧乙烷、环氧丙烷[J].化学分析计量,2021,30(12):1.
Yue Dalei,Zhang Zihao,Li Quanzhong,et al. Determination of ethylene oxide and propylene oxide in protective masks for children by purge and trap-gas chromatography-tandem mass spectrometry[J]. Chemical Analysis and Meterage,2021,30(12):1.
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