适体及其在分析检测中的应用
富波,范卓文
黑龙江中医药大学,哈尔滨 150040
Aptamer and Its Application in Analytical Testing
富波,范卓文
Heilongjiang University of Chinese Medicine, Harbin 150040, China
摘要:适体的出现使人们认识到核酸不仅可以作为遗传信息存储和转运的载体,还可以作为一种具有识别功能的分子。适体对目标物的识别具有高选择性和高亲和力,还有很多其它传统识别分子所不具备的优点,这使得其在分析检测领域得到关注和广泛应用。对适体的筛选过程、特点以及其在分析检测方面的主要应用进行综述。
Abstract:The appearance of aptamer raises the awareness of that nucleic acid not only can be used as carrier of genetic information storage and transportation, but also can be used as a kind of molecular with recognition function. The recognition of aptamer and its target has high selectivity and high affinity. Aptamer has many advantages that other traditional recognition molecules do not have, which makes it arouse strong concern and be widely used in the field of analytical testing. The selection process and characteristics of aptamer and its main application in analytical testing were reviewed.
关键词:适体;农药;药物;金属离子;微生物;蛋白质;生物毒素
Keywords:aptamer; pesticide; drug; metal ion; microorganism; protein; biotoxin
基金:黑龙江省教育厅科学技术研究项目
本文引用格式:
富波,范卓文.适体及其在分析检测中的应用[J].化学分析计量,2015,24(3):99-101.
FU B,FAN Z W.Aptamer and Its Application in Analytical Testing[J]. Chemical analysis and meterage,2015,24(3):99-101.
相似文章: